Genetic testing

Genetic testing

Genetic testing is the most advanced method for detecting the presence of traits (gene) to a disease. And there long before the onset of the disease, the risk is foreseen, to ensure preventive measures or additional targeted testing to detect such diseases . In many cases, although we are not able to develop the disease fully prevented, we are able to significantly reduce its consequences. Examination of the patient does not affect in any way , is merely a cotton swab swabs from the buccal mucosa , the result is known in a few weeks. Details on genetic testing are given below.

Currently available genetic tests

  • Celiac Disease
  • Blood clotting disorders

Principles of testing

By genetic testing is the analysis of genes that are associated with the disease, for which testing is conducted . Very simply monitors the occurrence of either a gene or a change . The first case is tested very presence of a particular gene ( genetic characteristics ), which according to the currently available knowledge occurs very frequently in relation to the desired disease or directly causes . Or being tested search so called mutations , ie variations in the gene. Very often it is a so-called point mutations , ie substitution of a single nucleotide in the DNA (deoxyribonucleic acid ) of the corresponding region of the gene investigated . This substitution can change the properties of proteins that DNA encodes , thereby increasing the risk of a particular disease or even cause the disease.

Interpretation of results

In most cases there is no positive evidence of disease, genetic testing , but provides information that the person tested has a higher risk for developing the disease. In such cases, it is rational recommended by the doctor to perform additional special testing or individual with the potential risk of long-term monitoring in a specialized clinic ( to dispenser ) . The negative result of the genetic analysis gives the strength of binding of a genetic defect on a particular disease , is likely to indicate that it is not about the disease . Genetic testing rule , based on the known risks and burdens of family doctor . In the case of own initiative to discuss with your healthcare professional interest to be tested . Similarly, evaluation of the results of genetic tests and determine further appropriate action belongs only to the doctor.

As testing takes place

The advantage of genetic screening is that it is a very safe, non-invasive, painless examination . The DNA testing is needed buccal swab of the oral cavity . In practice, the cotton swab on a stick Wipe the inside of the cheek . The thus obtained biological sample is then subjected to genetic testing. Test results are available in approximately 14 days. Before sampling is not required to follow any long-term measures , diet , and the like . 30 minutes prior to collection of the client should not eat or drink except plain carbonated water. Immediately before the sample is also recommended to rinse the mouth with still water. Sampling can be done at any time during working hours surgery.

Investigations are currently not covered by health insurance.

Current offer genetic testing:

Celiac Disease

DNA analysis of celiac disease

Blood clotting disorders

Increased formation of blood clots - DNA analysis of thrombophilic factors

Cooperation with

  • Faculty Hospital Olomouc
  • University Hospital Bulovka
  • l - ll Teaching Hospital in Prague
  • Perfect Clinic Prague